Abstract
AIM: To evaluate the effect of adding Aloe Vera nanoparticles encapsulated by chitosan nanospheres on glass ionomer for antibacterial activity and solubility.
MATERIALS AND METHODS: Forty samples were used in the study and divided into two groups according to the test (n = 20) for each group. The antibacterial activity of each group was tested using the agar diffusion test. The samples were dried in a desiccator for the solubility test until a constant weight was achieved. Then, the dried samples were weighed accurately using an analytical balance. This record is the initial weight (W1). Then, the samples were immersed in distilled water at a controlled temperature for 1 hour, 24 hours, and 7 days. The samples were weighed again to determine the weight after sorption.
RESULTS: The average inhibition zone diameter was 0.050 ± 0.009 mm for the control group and 3.44 ± 0.107 mm for the 15% GI-Aloe Vera (ECnS) group. This difference was statistically significant. Regarding solubility, the difference between groups was statistically significant (p = 0.000). At 1 hour, control recorded 0.714 ± 0.106, while GI-Aloe Vera (ECnS) 15% recorded a lower value of 0.504 ± 0.075. At 24 hours, control recorded (0.950 ± 0.142), while GI-Aloe Vera (ECnS) 15% recorded a lower value (0.670 ± 0.100). On day 7, the control recorded 1.187 ± 0.177, while GI-Aloe Vera (ECnS) 15% recorded a lower value of 0.838 ± 0.125.
CONCLUSION: Incorporating Aloe Vera nanoparticles improved the microbiological properties by inhibiting the growth of Streptococcus mutans (S. mutans) on the glass ionomer cement (GIC) and reducing solubility, making them more durable and effective for dental restorations.
CLINICAL SIGNIFICANCE: The incorporation of Aloe Vera nanoparticles encapsulated by chitosan nanospheres significantly enhanced the antibacterial properties of GIC against S. mutans and reduced solubility, potentially improving the material's clinical performance and longevity. How to cite this article: Elzoka AH, El Saeed SA, Abogabal AD, et al. Effect of Incorporation of Aloe Vera Nanoparticles Encapsulated by Chitosan Nanospheres on Antibacterial Properties and Solubility of Glass Ionomer. J Contemp Dent Pract 2025;26(9):860-867.