Feedback control systems could revolutionize the administration of prescription opioids.

Opioids pose significant risks of addiction due to the cyclical nature of serum opiate concentration associated with traditional dosing methods. Emerging technologies, including closed-loop feedback control systems, offer a promising solution by enabling dynamic, real-time microdosing that minimizes fluctuations in drug levels and reduces the risk of dependency. Drawing on advancements in biosensors and feedback systems used in other medical applications, these innovations could revolutionize pain management, potentially reducing opioid addiction rates by up to 87 percent compared to current oral administration methods.