Beyond the Norm: Recognizing Uncommon Presentations of Large Vessel Vasculitis.

Swain, Bishakha, Girija Sachdev, and Rohini Samant. 2025. “Beyond the Norm: Recognizing Uncommon Presentations of Large Vessel Vasculitis.”. The Journal of the Association of Physicians of India 73 (9S): 30-32.

Abstract

Large vessel vasculitis (LVV) is known to affect the aorta and its branches. Takayasu arteritis (TAK) is a well-recognized LVV. TAK typically manifests with limb claudication, syncope, angina, absent pulses and unequal blood pressure. These symptoms stem from fibrotic and irreversible processes like stenosis and contribute to morbidity and mortality. Early atypical presentations may lead to delayed diagnosis. This underscores the importance of early diagnosis to arrest inflammation and prevent permanent damage. We present three cases where LVV was identified in patients with unusual symptoms, emphasizing the necessity for a high index of suspicion among healthcare providers. This is especially crucial in the primary care setting where patients first encounter general practitioners.

Last updated on 09/17/2025
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